The use of transcranial magnetic stimulation for the treatment of anxiety and depressive disorders

Rassvet M.; Konovalova O.; Galushina E.

doi:10.14529/jpps240305

M. M. Rassvet 1) Krasnoyarsk State Medical University named after Prof. V.F. Voino-Yasenetsky (Partizan Zheleznyak str., 1, Krasnoyarsk, 660022, Russia); 2) Federal Siberian Research Clinical Centre under FMBA of Russia (Kolomenskaya str., 26/2, Krasnoyarsk, 660037, Russia) https://orcid.org/0009-0008-3614-9436 rassvet.maxim@gmail.com
O. N. Konovalova Federal Siberian Research Clinical Centre under FMBA of Russia (Kolomenskaya str., 26/2, Kras-noyarsk, 660037, Russia) https://orcid.org/0009-0008-8688-0569 tereshonokon@gmail.com
E. N. Galushina Krasnoyarsk State Medical University named after Prof. V.F. Voino-Yasenetsky (Partizan Zheleznyak str., 1, Krasnoyarsk, 660022, Russia) https://orcid.org/0000-0002-5628-0078 e.n.galushina@gmail.com

DOI: https://doi.org/10.14529/jpps240305

Keywords: transcranial magnetic stimulation, depression, anxiety disorders, dorsolateral prefrontal cortex, psychotherapy, treatment effectiveness, statistical analysis, mental disorders

Abstract

Introduction. Depression and anxiety disorders are prevalent mental illnesses, demanding the exploration of new, non-pharmacological treatment approaches. Transcranial magnetic stimulation (TMS), a non-invasive method, has shown promising results in managing these conditions. Aims. This study aims to assess the effectiveness of TMS applied to the dorsolateral prefrontal cortex (DLPC) in reducing symptoms of anxiety and depression among patients undergoing medical rehabilitation. Materials and methods. This study involved 20 patients from the Siberian Clinical Center of the FMBA of Russia, Rehabilitation Department No. 1, aged 50 to 80 years, divided into control (n = 10) and experimental (n = 10) groups. Anxiety and depression levels were assessed using Beck scales before and after the intervention. Patients in the experimental group received 10 daily sessions of TMS to the left DLPC (10 Hz, 120% of motor threshold, 3000 pulses). Results. The experimental group demonstrated statistically significant reductions in anxiety and depression scores after the TMS course compared to the control group. Conclusion. DLPC-targeted TMS is a promising treatment for anxiety and depressive disorders. Further research with larger sample sizes is needed to optimize treatment protocols and investigate long-term effects.

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Author Biographies

M. M. Rassvet , 1) Krasnoyarsk State Medical University named after Prof. V.F. Voino-Yasenetsky (Partizan Zheleznyak str., 1, Krasnoyarsk, 660022, Russia); 2) Federal Siberian Research Clinical Centre under FMBA of Russia (Kolomenskaya str., 26/2, Krasnoyarsk, 660037, Russia)

Clinical psychologist, lecturer at the Department of Clinical Psychology and Pedagogy with a postgraduate course

O. N. Konovalova , Federal Siberian Research Clinical Centre under FMBA of Russia (Kolomenskaya str., 26/2, Kras-noyarsk, 660037, Russia)

Neurologist-somnologist, head of the Department of Medical Rehabilitation No. 1

E. N. Galushina , Krasnoyarsk State Medical University named after Prof. V.F. Voino-Yasenetsky (Partizan Zheleznyak str., 1, Krasnoyarsk, 660022, Russia)

Candidate of Physical and Mathematical Sciences, Associate Professor of the Department of Medical Cybernetics and Computer Science

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